药物洗脱支架治疗头臂型大动脉炎的疗效评价

Effect of drug-eluting stent on brachiocephalic Takayasu arterities

目的评估药物洗脱支架（drug-elutingstent，DES）治疗头臂型大动脉炎的临床疗效。方法回顾性分析2010年3月至2011年4月采用DES治疗头臂型大动脉炎6例患者的临床资料，其中男2例，女4例，平均年龄（32±17）岁。对临床安全性、有效性进行分析。结果6例患者共9根血管置入DES，其中颈动脉4根，椎动脉3根，锁骨下动脉2根，手术进行顺利，未发生相关并发症。患者平均随访（13±4）个月，有2例患者共3根血管发生支架内再狭窄〉90％，无支架断裂、移位等并发症。结论DES在头臂型大动脉炎的治疗中有较好的安全性和有效性，积极有效地激素治疗是保证其远期通畅性的关键因素。

Objective To evaluate drug-eluting stent （DES） in the treatment of branehiocephalic Takayasu arterities （BCTA）. Methods From March 2010 to April 2011, six BCTA cases [ 2 males and 4 females, mean age （32 ＋ 17） years] were treated with DES at our department. The safety and effectivity of DES were analysed. Results There were 9 vessels including 4 carotid arteries, 3 vertebral arteries and 2 subclavian arteries, DES were implanted successfully without operation related complications. After （13 ＋ 4） months of follow up,2 cases with 3 arteries showed severe in-stent restenosis（ 〉 90% ）. There was no other complications such as stent fracture or displacement. Conclusions DES is safe and effective in treatin~ BCTA. and reaular zlucocorticoid therapy is important for lonz-term t）atencv of the DES.