眼部细菌感染病原学分析

Etiological analysis of ocular bacterial infection

目的回顾性总结分析眼部细菌培养的菌群分布及其变化规律。方法对2005-2011年住院患者分离的眼部4646例标本进行细菌培养及鉴定，对所有结果进行归纳总结。结果2005-2011年住院患者分离的眼部标本4646例，细菌培养阳性菌株1591例，平均阳性率34．24％。其中革兰阳性球菌占72．66％，革兰阳性杆菌占4．53％，革兰阴性球菌占2．07％，革兰阴性杆菌占20．74％。结论革兰阳性球菌和革兰阴性杆菌为眼部主要致病菌，革兰阳性球菌中以表皮葡萄球菌居首，且呈逐年上升趋势。革兰阴性杆菌以铜绿假单胞菌居首几年来波动不大，均排在各年细菌排名的前五位，了解本院眼部细菌菌种的分布与变化，对感染性眼病的预防与治疗具有重要意义。

Objective To analyze the flora distribution and its variation of eye bacterial culture in our hospital retrospectively. Methods Based on the separated 4646 eye specimens of the hospitalized patients from 2005-2011, grown bacterial culture, identified, and summarized all the results. Results In all the separated 4646 eye specimens of the hospitalized patients from 2005-2011, positive bacterial culture strains were 1591, which average positive rate was 34.24%. Among these, gram-positive cocci accounted fbr 72.66%, gram-positive bacilli 4.53%, gram-negative cocci 2.07% and gram-negative bacilli 20.74%. Conclusions Gram-positive cocci and gram-negative bacilli are major pathogens causing eye disease. Staphylococcus epidermidis is the largest share of gram-positive cocci, and showed an increasing trend. Pseudomonas aeruginosa is the main reason in gram-negative bacilli with little fluctuation in these few years and is ranked in the top live of the bacteria rankings in each year. To understand the eye bacteria distribution and variation in our hospital has a very important significance in the prevention and treatment of infectious eye disease.