医用乳酸菌对常用中草药的耐药性试验

Drug resistance test of medicinal lactic acid bacteria to common Chinese herbal medicines

目的研究医用乳酸菌对几种常用中草药的耐药性,为医用乳酸菌与中草药的临床合并应用提供理论依据。方法将中草药制成煎剂,通过琼脂扩散方法进行耐药性试验。结果 5种医用乳酸菌对黄连均表现出中度敏感,对黄芩表现微弱敏感。结论 5种医用乳酸菌对大部分中草药(包括有抗菌和抑菌作用的中草药)不敏感。

Objective To study the drug resistance of medicinal lactic acid bacteria to several common Chinese herbal medicines,and provide theoretical basis for clinical application of the combinations of herbs and lactic acid bacteria.Methods Drug resistance was detected by using agar diffusion test.Results The five kinds of medicinal lactic acid bacteria were all moderately sensitive to Rhizoma Coptidis and slightly sensitive to Scutellaria Baicalensis.Conclusion The five kinds of medicinal lactic acid bacteria are not sensitive to most Chinese herbal medicines including the herbs with have antimicrobial effect and antibacterial effects.