年轻妇女宫颈癌的临床特征及预后因素的分析

CLINICAL FEATURES AND PROGNOSIS OF CERVICAL CANCER IN YOUNG WOMEN

目的分析35岁以下年轻妇女宫颈癌(以下简称年轻宫颈癌)的发病趋势、病因、临床表现、治疗方法以及预后因素。方法对200例宫颈癌患者的临床资料进行回顾性分析。结果年轻宫颈癌临床表现以接触性阴道出血为主要表现,分期以ⅠA～ⅡA期为主,非鳞癌比例高,以手术治疗为主,ⅠA～ⅡA期年轻宫颈癌的2年复发率高于中老年组。结论年轻宫颈癌发病呈逐年上升趋势,临床及病理特征具有特殊性,预后差,较高的误诊率及复发率提示加强对年轻妇女的筛查,早诊断早治疗,是影响宫颈癌预后的重要因素。

Objective To investigate the prevalence, etiology, clinical presentation and pathological features, treatment and prognosis of cervical cancer in young women under 35 years old. Methods The clinical information of 80 patients under 35 years old were retrospectively analyzed, at the same time, 120 middle/ senile patients with cervical cancer from 36 to 75 years old as a control group. Results The primary clinical presentation of young patients with cervical cancer was contact bleeding of vagina, and nonsquamous carcinoma possessed a large percentage. The main treatment for the cervical cancer patients was surgery. The 2 - year recurrence rate in young patients in early IA-IIA stage was higher than that in Control group. Con- clusions There is an increasing prevalence of cervical cancer in women under 35 years old. The prognosis in study group is poorer than that in control group, which is related to the increasing proportion of clinic stage and pathological features in study group. It is key point for us to screen young married women to find the CIN and the carcinoma at the early stage.