摘要
氯巴占为1,5-苯二氮类药物,具有抗癫痫作用,FDA于2011年10月21日批准其用于难治性癫痫———林-戈综合征(Lennox-Gastaut syndrome)的辅助治疗。本文通过Medline对氯巴占进行文献检索,并对其药理作用、药动学、药物相互作用、临床研究和安全性进行了综述。
Clobazam, a 1,5-benzodiazepine, possesses antiepileptic activity. It has been approved by the FDA for treatment of Lennox-Gastaut syndrome, one of the refractory epilepsies, in October 21th, 2011. Literature search was conducted by searching MEDLINE with the key words clobazam. The pharmacology, pharmacokinetics, drug interactions, clinical trials and side effects of clobazam were reviewed in this paper.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2013年第4期375-378,共4页
Chinese Journal of New Drugs
关键词
氯巴占
林-戈综合征
药理作用
临床研究
clobazam
Lennox-Gastaut syndrome
pharmacology
clinical study