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前动力蛋白与妊娠

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摘要 前动力蛋白(prokineticin,PROK)是多功能性分泌蛋白家族成员之一,其受体是其同源的G蛋白偶联受体。PROK系统由PROK1及其受体、PROK2及其受体组成。PROK与受体结合引发信号转导,具有调节平滑肌收缩、诱导血管生成及膜孔形成、免疫调节、低氧调控等作用。PROK及其受体在妊娠的不同阶段表达水平不同,与妊娠维持、分娩发动等生理妊娠及早产、复发性流产、异位妊娠、子痫前期等病理妊娠密切相关。
出处 《中华围产医学杂志》 CAS 北大核心 2013年第2期114-117,共4页 Chinese Journal of Perinatal Medicine
基金 福建省科技计划重点项目(2009YO008) 福建省卫生厅医学创新课题(2009-CXB32)
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