摘要
Klotho基因是20世纪末发现的具有抗衰老功能的新型基因，近些年来发现其在某些肿瘤中表达下调，如胃癌、肺癌、乳腺癌、子宫颈癌、皮肤癌、膀胱癌、结肠癌等，提高Klotho基因在这些癌细胞株中的表达可抑制肿瘤复制扩散能力，甚至使肿瘤细胞趋向凋亡，因此推测Klotho基因可能是一种具有抗肿瘤功能的新型基因。
Klotho gene is a new gene found in the 20 century, which has a anti-aging function. Researchers people find that its expression in some tumors is down-regulated, such as in gastric cancer, lung cancer, breast cancer, cervical cancer, skin cancer, bladder cancer, colon cancer and so on. The ability of tumor＇s replication and invasion could be inhibited through increasing the expression of Klotho gene, even be trended to apoptosis. So that the Klotho gene may be a new gene which has a anti-tumor function.
出处
《肿瘤研究与临床》
CAS
2013年第1期67-69,共3页
Cancer Research and Clinic
