二代测序在急性髓系白血病中的应用

Application of next-generation sequencing in acute myeloid leukemia

二代测序（NGS）目前被广泛用于急性髓系白血病（AML）的检测，由于其具有高通量、高灵敏度特性，为AML的诊断、治疗与预后判断带来了新的进展。在第54届美国血液学会（ASH）年会上关于NGS在AML中的应用有大量的报道，反映了NGS这门新技术在现代血液病诊治中的重要地位及对血液病未来发展的影响。

Next-generation sequencing （NGS） platforms have recently evolved to provide an accurate and comprehensive means for the detection of molecular mutations in acute myeloid leukemia（AML）. The 54th ASH annal meeting reported lots of studies on NGS in AML, reflect the important role of the NGS technology in modern diagnosis and treatment of blood diseases and the impact on the future development of the blood disease.