抑郁症、焦虑症、强迫症患者主观幸福感比较

The subjective well-being of patients with major depression disorder,anxiety disorders and obsessive-compulsive disorder

目的:比较抑郁症、焦虑症、强迫症患者主观幸福感的异同,探索主观幸福感稳态理论对三者的适用性。方法:对门诊和病房的抑郁症(n=79)、焦虑症(n=53)、强迫症(n=48)患者,及正常对照组(n=57)被试进行24项汉密顿抑郁量表(HAMD)、幸福感指数问卷测评分析。结果:①抑郁症组、焦虑症组、强迫症组与正常对照组的主观幸福感差异具有统计学意义(F=16.55,P<0.01)。②抑郁症组的主观幸福感得分与绝望感因子分呈负相关(P<0.01),焦虑症组与认知因子分、睡眠因子分、绝望感因子分呈负相关(P<0.05),强迫症组分别与HAMD总分、日夜变化因子分、迟缓因子分、绝望感因子分呈负相关性(P<0.05)。③逐步回归分析结果表明,抑郁症患者的绝望感因子和焦虑因子、焦虑症患者的认知因子和睡眠因子、强迫症患者的绝望感因子是影响各自主观幸福感的主要因素。结论:抑郁症、焦虑症、强迫症患者的主观幸福感均低于正常人;抑郁症患者的主观幸福感更低;均与抑郁症状有关。

Objective： To compare the difference of subjective well-being between patients with major depression disorder （ MDD）, anxiety disorders （ AD ） and obsessive-compulsive disorder （ OCD ） and explore the applicability of the Theory of subjective well-being homeostasis to MDD, AD and OCD. Method： Patients with MDD （ n = 79）, AD （ n = 53 ） and OCD （ n = 48 ） and control group （ n = 57 ） were measured with Hamilton depression scale（HAMD） and Subjective Well-being Index Questionnaire. Results：①There were significant differences in the scores of subjective well-being index between patients groups （MDD,AD and OCD）and con- trol group （ F = 16. 55, P 〈 0.01 ）. ②In MDD group,The scores of subjective well-being index and the despera- tion factor scores are negatively correlated （ P 〈 0.01 ） ; In AD group, The scores of subjective well - being index and the cognition factor scores, the sleep factor scores, the desperation factor scores are negatively correlated （ P 〈 0.05） ;In OCD group, The scores of subjective well-being index and the HAMD scores, the diurnal variation scores, the retardation scores, the desperation factor scores are negatively correlated （ P 〈 0.05 ）. ③Stepwise re- gression analysis indicated the desperation factor and the anxiety factor significantly affect the level of subjective well-being in MDD group; the cognition factor and the sleep factor significantly affect the level of subjective well- being in AD group ; the desperation factor significantly affect the level of subjective well-being in OCD group. Conclusion： Subjective well - being in patients with MDD, AD and OCD is lower than control people, and asso- ciated with depressive symptoms.