血液病或肿瘤患儿生存质量及行为问题的初步调查

Quality of life and behavior problems in children with hematologic diseases or tumor

目的:检测血液病/肿瘤患儿与普通疾病患儿的生存质量及行为差异。方法:运用儿童生存质量普适性核心量表父母报告(PedsQLTM4.0)及Achenbach儿童行为评定量表(CBCL)对30例年龄在6～11岁血液病/肿瘤患儿及34例呼吸系统疾病患儿进行心理评估;采用抑郁自评量表(SDS)、焦虑自评量表(SAS)、家庭环境量表中文版(FES-CV),对血液病/肿瘤患儿家长进行心理、家庭环境评估。结果:血液病/肿瘤患儿生存质量显著低于对照组(P=0.000),生理功能、情感功能、社会功能、学校表现均显著低于对照组(P均<0.01)。血液病/肿瘤男性患儿躯体诉述、违纪得分高于对照组(P均<0.05);女性患儿社交退缩高于对照组(P<0.05)。患儿的生存质量与家长的心理卫生状况及家庭环境情况有显著的相关性。结论:血液病/肿瘤患儿可能存在较多的生存质量及异常行为问题,在治疗原发病的同时,心理干预仍是必要的。

Objective： To evaluate caregiver-reported health-related quality of life （ PedsQLTM 4.0 ） and behaviors of children with hematologic disease or tumor. Method ： Caregivers of 30 children with hematologic disease or tumor aged 6 - 11 years and 34 children with respiratory disease completed the child behavior check- list （CBCL） ,the pediatric quality of life inventory （PedsQLrM4.0）. Family members of children with hemato- logic disease or tumor were evaluated with self-rating depression scale, self-rating anxiety scale and family envi- ronment scale. Results：Children on therapy for hematological tumor have significantly lower QoL compared to control group（ P = 0. 000）. Patients with hematological tumor exhibited more problems than patients with respir- atory disease in the physical, emotional, social and school function （ all P 〈 0. 01 ）. The abnormal behavior in the boys with hematological tumor mainly included somatic complaints and rule-breaking behaviors （ all P 〈 0.05 ）, while in the girls induded social withdraw. There was a significant correlation between Qol score of children with malignancies and their parents mental health status. There also was a significant correlation between QoL score of children with malignancies and the family environment. Conclusion： Children with hematologic disease or tumor probably have more QoL and behavioral problems. Intervention and efforts promoting adjustments are still required.