七氟烷吸入麻醉在脑性瘫患儿腰椎穿刺干细胞治疗中的应用

Application of anesthesia of Sevoflurane to cerebral palsy children during operation of spinal puncture stem cell therapy

目的探讨七氟烷吸入麻醉在脑性瘫患儿腰椎穿刺干细胞治疗中的临床效果及实用性。方法选取60例年龄1～6岁行腰椎穿刺干细胞治疗的脑性瘫患儿,ASAⅠ～Ⅱ级,分成两组(n=30),七氟烷组(Ⅰ组)和氯胺酮组(Ⅱ组),观察两组诱导和苏醒时间,诱导的依从性、术中体动和苏醒期躁动的发生率。结果与Ⅱ组比较,Ⅰ组能较好地接受诱导,诱导、苏醒时间较短,术中体动及苏醒期躁动发生率较低(P<0.05)。结论七氟烷吸入麻醉具有麻醉诱导时间短,苏醒快,不良反应少,能较好地应用于脑性瘫患儿腰椎穿刺干细胞治疗。

Objective To analyze the efficacy and practicability of anesthesia of Sevoflurane in cerebral palsy children during the operation of spinal puncture stem cell therapy. Methods Sixty cerebral palsy children （ ASA Ⅰ - Ⅱ ） aged from 1 to 6 years old with the operation of spinal puncture stem cell therapy were randomly divided into Sevoflurane group （ Group Ⅰ , n = 30 ） and Ketamine group （ Group Ⅱ , n = 30）. Such parameters, as induction time, recovery time, and incidences of compliance in induction, movement during operation and agitation, were recorded. Results The compliance of Group Ⅰ was better than that of Group Ⅱ , the induction time and recovery time of Group I were shorter than that of Group Ⅱ , the incidences of movement during operation and agitation of Group Ⅰ were less than that of Group Ⅱ （P 〈 0.05）. Conclusion Anesthesia with Sevoflurane is suitable for cerebral palsy children during the operation of spinal puncture stem cell therapy with quicker induction and recovery time and with less adverse effect.