氟嗪酸(Ofloxacin)治疗复杂性尿路感染和腹膜透析腹腔感染

Ofloxacin Treatment of the Complicated Urinary Tract Infections and CAPD Peritonitis

口服氟嗪酸治疗复杂性尿路感染20例和维持性腹膜透析(CAPD)引起腹腔感染者10例,获明显效果,细菌培养转阴率为88％～90％,除1例外,症状均消失。

Two studies of oral treatment of patients with complicated urinary tract infections and peritonitis in CAPD with ofloxacin are described. The first study included 20 patients treated with ofloxacin 400mg daily for a total of 7 days. In the second Study of 10 peritonitis episodes, the treatment was ofloxacin 400mg followed 300mg daily for a total of 13 days. The causative organisms were eradicated in 88%～90% in these patients. Clinical responresponse was favorable in all except one patient of peritonitis. One patient discont inued therapy as a result of skin rash. These studies indicated that ofloxacin is very effective in the therapy of complicated infeetions and CAPD peritonitis.