樟树籽仁油合成癸/月桂酰基谷氨酸钠工艺研究

Synthesis of sodium caprinoyl /lauroyl glutamate with camphor tree seed kernel oil

以樟树籽仁油为原料,通过皂化、酰氯化,碱性条件下与谷氨酸钠反应生成癸/月桂酰基谷氨酸钠盐。研究反应温度、pH、反应时间、丙酮与水体积比以及谷氨酸钠与癸/月桂脂肪酰氯摩尔比对癸/月桂酰基谷氨酸钠合成率的影响。得出最佳合成条件为:反应温度45℃,反应时间3 h,pH10～11,丙酮与水体积比2∶1,谷氨酸钠与癸/月桂脂肪酰氯摩尔比2∶1。在此条件下,癸/月桂酰基谷氨酸钠的合成率为89.2%。经质谱及红外光谱分析,确定产物为癸/月桂酰基谷氨酸钠。

Sodium caprinoyl/lauroyl glutamate was synthesized under alkaline condition with sodium gluta- mate and capric/lauric fatty acid chloride produced from camphor tree seed kernel oil by saponification and acyl chlorination. The effects of reaction temperature, pH, reaction time, volume ratio of acetone to water and molar ratio of sodium glutamate to capric/lauric fatty acid chloride on the synthesis rate of sodi- um caprinoyl/lauroyl glutamate were studied. The optimal synthesis conditions were as follows：reaction temperature 45 ~C ,reaction time 3 h,pH 10 - 11 ,volume ratio of acetone to water 2：1 and molar ratio of sodium glutamate to capric/lauric fatty acid chloride 2： 1. Under the optimal synthesis conditions, the syn- thesis rate reached 89. 2%. The product was determined as sodium caprinoyl/lauroyl glutamate by infra- red spectrometry and mass spectrometry.