银杏达莫注射液治疗急性脑梗死对照观察

The Controlled Observation of Ginkgo Leaf Extract and Dipyridamole Injection in Treating Acute Cerebral Infarction

[目的]观察银杏达莫注射液治疗急性脑梗死疗效。[方法]将80例急性脑梗死患者随机分为两组,治疗组40例使用银杏达莫注射液20mL加入0.9%氯化钠注射液250mL,每日静滴1次;对照组40例使用丹参注射液30mL加入0.9%氯化钠注射液250mL,每日静滴1次。两组共治疗14d后判定疗效,观测治疗前后血常规、尿常规、便常规、出凝血时间、血脂、同型半胱氨酸、血小板聚集率、纤维蛋白原等血液流变学指标以及肝肾功能。[结果]治疗组总有效率90.00%,对照组总有效率65.00%,治疗组优于对照组(P<0.05),两组治疗前后血液流变学评分均有改善(P<0.05),治疗组优于对照组(P<0.05)。[结论]银杏达莫注射液治疗急性脑梗死疗效满意,无不良反应。

[ Objective] To observe Ginkgo leaf extract and dipyridamole injection treatment of acute cere- bral infarction. [ Methods ] 80 cases of acute cerebral infarction were randomly divided into two groups： the treatment group of 40 patients, application Ginkgo leaf extract and dipyridamole injection 20mL, adding 0.9% sodium chloride injection 250mL intravenous infusion once a day;the control group, 40 cases with Salvia injec- tion 30mL, adding 0.9% sodium chloride injection 250mL, daily intravenous infusion of once. Two groups of the therapeutic efficacy were evaluated after 14 days. The blood, urinary and stool routine test, BT, CT, blood lipids, HCY, AGG, FBG and hemorheology indexes as well as hepatic and renal function were all observed be- fore and after treatment. [Results]The treatment group and control group total efficiency respectively of 90% and 65% , The treatment group was superior to control group（ P 〈0.05 ） , two methods before and after treat- ment both have the effect of improving some blood rheology indexes （ P 〈 0.05 ） The treatment group was supe- rior to control group（P 〈0.05 ）. [ Conclusion] Ginkgo leaf extract and dipyridamole injection is effective in the treatment of acute cerebral infarction, and not have debilitating side - effects.