益气养阴汤加减治疗糖尿病性胃轻瘫随机平行对照研究

The Change of Supplementing Qi and Nourishing Yin Decoction Treatment of Diabetic Gastroparesis Randomized Controlled Study

[目的]观察益气养阴汤加减治疗糖尿病性胃轻瘫疗效。[方法]将120例糖尿病性胃轻瘫患者,依就诊顺序随机分为治疗组和对照组,每组60例。两组患者均予糖尿病饮食及药物控制血糖。治疗组使用益气养阴汤加减(药用太子参、黄芪、山药、陈皮、石斛、白术、旋复花等),1剂/d,水煎,早晚2次空腹服用。对照组使用西沙比利10mg,tid,饭前30min服用。观测治疗前后症状总分数,并检测空腹血糖、餐后2h血糖。治疗2个疗程判定疗效。[结果]治疗组总有效率优于对照组(P<0.05);治疗组空腹血糖、餐后2h血糖治疗后均有不同程度改善,治疗后治疗组优于对照组(P<0.05);治疗组各项症状治疗后均有不同程度改善,治疗后治疗组优于对照组(P<0.05)。[结论]益气养阴汤加减治疗糖尿病性胃轻瘫疗效满意。

[ Objective ] To observe the therapy of Supplementing Qi and Nourishing Yin Decoction on the effect of diabetic gastroparesis. [Methods] 120 cases of diabetic gastroparesis patients, according to the order were randomly divided into the treatment group and the control group, 60 cases in each group. Two groups were treated by diabetic diet and drug control of blood glucose. The treatment group used the Supplementing Qi and Nourishing Yin Decoction （ Radix Astragali, Radix Pseudostellariae, Medicinal Dendrobium, tange- rine peel, yam, white atractylodes rhizome, elecampane, etc. ） , 1 doses/day, by water simmer, twice on morning and evening with an empty stomach. The control group using the cisapride tablels 10mg, tid,taking medicine before ante cibum in 30min. To observe the symptoms total scores before and after treatment, and to test the fasting blood glucose, 2hours postprandial blood sugar, Comparing the curative effect after 2 treatment courses. [ Results ] The total effective rate of treatment group is better than control group （ P 〈 0.05 ） ; The fasting blood glucose, postprandial blood sugar after 2hours treatment improved in different degrees of the treatment group, after treatment in the treatment group effects than in control groups （ P 〈 0.05 ） ; the treat- ment group after treatment the symptoms improved in different degrees, after treatment in treatment group effects than in control group＇s （P 〈0.05 ）. [ Conclusion] The Supplementing Qi and Nourishing Yin Decoc- tion in the treatment of diabetic gastroparesis with satisfactory results.