摘要
药物成瘾不仅危害成瘾者自身的身体和精神健康,还会引起严重的社会、公共卫生和经济问题。药物成瘾之所以能造成如此严重的危害,主要是因为难于克服的心瘾导致的高复吸率。在本文中,作者就药物成瘾的流行病学特点、与药物成瘾相关的一些概念、机体对毒品易感性的生物学基础和成瘾的生物学本质与防复吸药物研发策略加以综述。
Drug addiction not only induces a lot of serious body and psychological damage to addicts themselves, but also causes many severe sociological, public healthy and economic problems. The reasons for drug addiction to induce so severe hazards are the high relapse rate induced by psychological dependence very difficult to be overcome. The following points are going to be reviewed in the text, inclu- ding epidemiological characteristics of drug addiction, some concepts to be related to drug addiction, biological basis of organism suscepti- bility to drugs and biological entity of drug addiction as well as strategies for research and development of anti-relapse drugs.
出处
《中国药物滥用防治杂志》
CAS
2013年第1期1-6,19,共7页
Chinese Journal of Drug Abuse Prevention and Treatment
基金
国家973项目(2009CB522008)
国家科技支撑计划项目(2012BAI01B07)
关键词
药物成瘾
生物学本质
易感性
复吸
Drug addiction
Biological entity
Susceptibility
Relapse
