摘要
目的:评价我院临床药师干预前、后Ⅰ类切口手术围术期抗菌药的应用情况与效果比较。方法:对我院2010年7~12月和2011年7~12月Ⅰ类切口手术预防用抗菌药的使用率、应用种类与频次、给药时机、用药时限、费用等进行统计分析。结果:实施药学干预后,我院Ⅰ类切口手术预防用抗菌药使用率由100%降至48.33%,第1代头孢菌素应用率由0升至63.79%;术前0.5~2 h预防用抗菌药比例由17.92%提高至95.59%;术后用抗菌药时间≤24 h的比例由23.33%提高至81.03%;平均用药时间由4.5 d缩短至1.9 d;平均抗菌药费用由635.69元降至256.57元。结论:实施药学干预可显著提高围术期抗菌药合理应用,对合理使用抗菌药有积极促进作用。
Objective:To evaluate the application and effects of antibiotics used before and after pharmaceutical interference by clinical pharmacists during the preoperative period of type I incision operation. Methods:The patients' statistics, varieties, frequency, time of drug delivery, administration duration and antibiotics expenses were gathered and analyzed for their type I incision operations from July to December of 2010 and from July to December of 2011. Results: After the pharmaceutical interference, the cephalosporin (first generation) used in our hospital was increased from 0 to 63.79%. The ratio covered by the preventive antibiotics that were used O. 5 to 2 hours before the operation was increased from 17.92% to 95.59%. The ratio for the duration not more than 24 hours of antibiotics administration was increased from 23.33% to 81.03%. The average drug administration time was shortened from 4.5 days to 1.9 days. The average expense for antibiotics was decreased from 635.69 yuan to 256.57 yuan. Conclusion:The implementation of pharmaceutical inter- ference could significantly facilitatethe reasonable application of antibiotics during the preoperative period, thus boosting the safe, effective, reasonable and economic administration of drug for patients.
出处
《药物流行病学杂志》
CAS
2013年第2期81-83,共3页
Chinese Journal of Pharmacoepidemiology
关键词
抗菌药
干预
I类切口手术
围手术期
合理用药
Type I incision operation
Antibiotics
Interference
Rational drug use