活血化瘀法治疗慢性阻塞性肺疾病急性加重期37例总结

Clinical efficacy of blood circulation-activating and blood stasis-removing traditional Chinese medicine preparation in patients with acute exacerbation of chronic obstructive pulmonary disease: a report of 37 cases

目的:观察活血化瘀中药制剂对慢性阻塞性肺疾病(慢阻肺)急性加重期的临床疗效。方法:将该病患者76例随机分为对照组39例和治疗组37例,对照组采用常规治疗,治疗组在对照组治疗的基础上加用活血化瘀中药制剂治疗。结果:治疗组对于C反应蛋白、肺功能及PO2的改善均明显高于对照组,差异有统计学意义(P<0.05,P<0.01);临床总有效率治疗组为91.89%,对照组为84.61%,两组比较差异有统计学意义(P<0.05)。结论:活血化瘀法中药制剂对慢阻肺急性加重期疗效确切。

Objective： To observe the clinical efficacy of blood circulation -activating and blood stasis -remo- ving traditional Chinese medicine （TCM） preparation in the patients with acute exacerbation of chronic obstructive pulmonary disease （COPD）. Methods ： Seventy - six patients with acute exacerbation of COPD were randomly di- vided into control group （n = 39） and treatment group （n = 37）. The control group received conventional treat- ment, while the treatment group was given blood circulation -activating and blood stasis -removing TCM prepara- tion in addition to the conventional treatment. Results： The treatment group showed significantly more improvement in C - reactive protein level, pulmonary function, and partial pressure of oxygen than the control group （ P 〈 0.05 or P 〈0.01 ）. The total effective rate was 91.89% in the treatment group, compared with 84.61% in the control group （P 〈 0.05 ）. Conclusion： Blood circulation- activating and blood stasis -removing TCM preparation has good clinical efficacy in the patients with acute exacerbation of COPD and shows promise for clinical application.