在离子液体介质中壳聚糖席夫碱衍生物的合成与表征

Synthesis and Characterization of Chitosan Schiff Base Derivatives in Ionic Liquid

以水杨醛(SA)为改性试剂,在离子液体1-丁基-3-甲基咪唑氯盐(BmimCl)介质中对壳聚糖(CS)进行了席夫碱化改性研究.考察了反应条件(反应物摩尔比、反应温度和反应时间)对产物取代度的影响,得到的最佳反应条件为:0.15 g壳聚糖溶解于10 g BmimCl中,壳聚糖中氨基与水杨醛摩尔比为1∶2.5,反应温度为80℃,反应时间为2 h.在最佳反应条件下,壳聚糖水杨醛席夫碱衍生物的取代度可达29.2%.利用红外、核磁及XRD等表征技术对产物进行了表征,并在最佳试验条件下合成了系列壳聚糖席夫碱衍生物.

Chitosan Schiff base derivatives were synthesized by the condensation reaction of chitosan and salicylaldehyde in an ionic liquid, 1-butyl-3-methylimidazolium chloride （BmimC1）. The effect of some reac-tion conditions, such as the molar ratio of free amino group to salicylaldehyde, reaction temperature and reac-tion time on the degree of substitution （DS） has been investigated. The DS could be reached 29.2% at the optional condition（0.15 g chitosan dissolved in 10 g BmimC1, the molar ratio of free amine group to salicylal- dehyde of 1 ： 2.5, a reaction temperature of 80 ℃ , and reaction time of 2 h）. The product was characterized by Fourier transform infrared （FTIR） , nuclear magnetic resonance （NMR） , and X-ray diffraction （XRD） , respectively. A series of ehitosan sehiff base derivatives was synthesized under the optimal conditions.