期刊文献+

小儿肺动脉高压的靶向治疗研究进展 被引量:11

原文传递
导出
摘要 肺动脉高压(PH)是以肺动脉压力和肺血管阻力升高为特征的临床血流动力学症候群,可导致右心衰竭和死亡。近年来,小儿PH靶向治疗的研究越来越受到重视,且得到了较快的发展。现就最近关于小儿PH的定义、分类、流行病学、诊断及治疗进展进行介绍。
出处 《中华实用儿科临床杂志》 CAS CSCD 北大核心 2013年第1期7-9,共3页 Chinese Journal of Applied Clinical Pediatrics
  • 相关文献

参考文献36

  • 1Hassoun PM,Adnot S. Update in pulmonary vascular diseases 2011[J].American Journal of Respiratory and Critical Care Medicine,2012,(11):1177-1182.
  • 2Simonneau G,Robbins IM,Beghetti M. Updated clinical classification of pulmonary hypertension[J].Journal of the American College of Cardiology,2009,(Suppl 1):43-54.
  • 3Badesch DB,Champion HC,Scanchez MA. Diagnosis and assessment of pulmonary arterial hypertension[J].Journal of the American College of Cardiology,2009,(Suppl 1):55-65.
  • 4Ivy D. Advances in pediatric pulmonary arterial hypertension[J].Current Opinion in Cardiology,2012,(02):70-81.
  • 5Berger RM,Beghetti M,Humpl T. Clinical features of paediatric pulmonary hypertension:a registry study[J].The Lancet,2012,(9815):537-546.
  • 6Barst R J,Ertel SI,Beghetti M. Pulmonary arterial hypertension:a comparison between children and adults[J].European Respiratory Journal,2011,(03):665-677.
  • 7Cerro M J,Abman S,Diaz G. A consensus approach to the classification of pediatric pulmonary hypertensive vascular disease:report from the PVRI Pediatric Taskforce,Panama 2011[J].Pulm Circ,2011,(02):286-298.
  • 8张清友,杜军保.肺动脉高压的治疗现状与进展[J].临床儿科杂志,2010,28(7):607-610. 被引量:22
  • 9Tissot C,Ivy DD,Beghetti M. Medical therapy for pediatric pulmonary arterial hypertension[J].Journal of Pediatrics,2010,(04):528-532.
  • 10Barst RJ,Maislin G,Fishman AP. Vasodilator therapy for primary pulmonary hypertension in children[J].Circulation,1999,(09):1197-1208.

二级参考文献30

  • 1Ma M, Gauvreau K, Allan CK, et al. Causes of death after congenital heart surgery. Ann Thorac Surg, 2007, 83 : 1438-1445.
  • 2Hawort SG. The management of pulmonary hypertension in children. Arch Dis Child, 2008, 93:620-625.
  • 3Hsu HH, Chen JS, Chen RJ, et al. Long-term outcome and effects of oral bosentan therapy in Taiwan Residents patients with advanced idiopathic pulmonary arterial hypertension. Respir Med, 2007, 101 : 1556-1562.
  • 4Lammers AE, Hislop AA, Flynn Y, et al. The 6-minute walk test: normal values for children of 4-11 years of age. Arch Dis Child, 2008, 93:464-468.
  • 5Keogh AM, McNeil KD, Wlodarczyk J, et al. Quality of life in pulmonary arterial hypertension: improvement and maintenance with bosentan. J Heart Lung Transplant, 2007, 26 : 181-187.
  • 6Galie N, Beghetti M, Gatzoulis MA, et al. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation, 2006, 114 : 48-54.
  • 7Barst R, Ivy D, Dingemanse J, et al. Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension. Clin Pharmacol Ther, 2003, 73:372-382.
  • 8Rosenzweig EB, Ivy DD, Widlitz A, et al. Effects of long-term bosentan in children with pulmonary arterial hypertension. J Am Coll Cardiol, 2005, 46:697-704.
  • 9Haworth SG, Hislop AA. Treatment and survival in children with pulmonary arterial hypertension: the UK Pulmonary Hypertension Service for Children 2001-2006. Heart, 2009, 95:312-317.
  • 10Votava-Smith JK, Perens GS, Alejos JC. Bosentan for increased pulmonary vascular resistance in a patient with single ventricle physiology and a bidirectional Glenn shunt. Pediatr Cardiol, 2007, 28:314-316.

共引文献33

同被引文献144

  • 1陆权.儿童社区获得性肺炎管理指南(试行)(上)[J].中华儿科杂志,2007,45(2):83-90. 被引量:604
  • 2何振华,戴爱国,张秀峰,谭小武.缺氧诱导因子1α和诱导型一氧化氮合酶基因在缺氧性肺动脉高压大鼠发病过程中的表达(英文)[J].中国组织工程研究与临床康复,2007,11(36):7290-7294. 被引量:13
  • 3Hassoun PM,Adnot S. Update in pulmonary vascular disease 2011[J].American Journal of Respiratory and Critical Care Medicine,2012,(11):1177-1182.
  • 4O'Callaghan DS,Savale L,Montani D. Treatment of pulmonary arterial hypertension with targeted therapies[J].Nat Rev Cardiol,2011,(09):526-538.
  • 5孙波;刘文利.右心导管测定肺动脉压力的实验方法[J]中国医学科学院学报,1984(06):465-467.
  • 6Chemla D,Hervé P. Estimation of mean pulmonary artery pressure:simpler than expected[J].CHEST,2008,(03):592-593.
  • 7Leblanc N,Ledoux J,Saleh S. Regulation of calcium-activated chloride channels in smooth muscle cells:a complex picture is emerging[J].Can J Physiol Pharmaco1,2005,(07):541-556.
  • 8Sun H,Xia Y,Paudel O. Chronic hypoxia-induced upregulation of Ca2 +-activated C1-channel in pulmonary arterial myocytes:a mechanism contributing to enhanced vasoreactivity[J].JOURNAL OF PHYSIOLOGY,2012,(15):3507-3521.
  • 9Tajsic T,Morrell NW. Smooth muscle cell hypertrophy,proliferation,migration and apoptosis in pulmonary hypertension[J].Compr Physiol,2011,(01):295-317.
  • 10Soon E,Holmes AM,Treacy CM. Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension[J].CIRCULATION,2010,(09):920-927.

引证文献11

二级引证文献139

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部