肾病综合征患儿庚型肝炎病毒感染情况的分析

Prevalence of hepatitis G virus infections in children with nephrotic syndrome

目的 :调查庚型肝炎病毒 ( HGV)在肾病综合征患儿中的感染分布。 方法 :115例患儿均为我科确诊的原发性肾病综合征住院患儿 ,另取 187例同期上呼吸道感染患儿 ,采取外周血 2 m l,用 RT- PCR方法检测 HGVRNA。 结果 :在 15 5例肾病综合征患儿中有 11例 ( 7.1% )存在 HGV感染 ,在 187例正常对照儿童中仅有 3例( 1.6 % )存在 HGV感染 ,两者具有较明显的差异。 结论 :肾病综合征患儿的 HGV感染率明显高于普通儿童 。

Objectives:To survey hepatitis G virus (HGV) infections in children with nephrotic syndrome. Methods:One hundred and fifteen patients with established diagnosis of nephrotic syndrome were from our inclinic.Another 187 children with upper respiratory infections served as control.Two milliliters of blood was taken from these patients to examine HGV RNA by RTPCR methods. Results:Of the total 115 patients with nephrotic syndrome,11 patients' HGV were positive(7.1%),otherwise HGV infection rate was only 1.6% (3 cases in the controls).There were significant difference between two groups. Conclusions:HGV infection rate is higher in nephrotic syndrome than in normal children.The nephrotic patients are the high risk populations of HGV infections.