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伊曲康唑口服溶液的制备与质量控制 被引量:1

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摘要 目的建立伊曲康唑口服溶液的制备工艺与质量控制方法。方法利用羟丙基-β-环糊精对伊曲康唑的包合作用制备,用紫外分光光度法测定伊曲康唑的含量。结果制备的伊曲康唑口服溶液外观澄清、透明、质量稳定。伊曲康唑质量浓度在4.5-36μg/mL范围内与吸光度线性关系良好平均回收率98.2%,RSD=0.74%。结论该制剂处方工艺及质量控制方法合理、科学,适用于产业化及其质量控制。
出处 《中国药业》 CAS 2012年第A02期6-6,共1页 China Pharmaceuticals
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