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心功能不全患者脑钠肽前体与心功能分级和左室射血分数相关 被引量:2

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摘要 目的:探讨氨基末端脑钠肽前体(NT-proBNP)与心功能不全分级及心脏左室射血分数(LVEF)之间的相关和NT-proBNP检测在心衰患者中的预测效应。方法:对116例心衰患者进行心功能不全分级,同时检测NT-proBNP和超声检查心脏左室射血分数,将3种指标进行比较、相关和回归分析。结果:心功能不全Ⅱ级与Ⅲ级之间、Ⅲ级与Ⅳ级NT-proBNP和LVEF均存在统计学差异(P<0.05、0.01),NT-proBNP与LVEF相关系数r=-0.7069,NT-proBNP与心功能不全分级的相关系数r=0.8106,回归分析显示,NT-proBNP可以解释LVEF49.94%的变异、可以解释或预测65.7%的心功能不全变化。结论:脑钠肽前体可以作为一个较好的预测心功能不全程度的指标。
出处 《中国社区医师(医学专业)》 2013年第4期126-127,共2页
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