纳米银与纳米氧化锌混合物的抗菌活性

The antibacterial activity of the mixture of nano Ag and nano ZnO

采用常温还原法合成纳米银及微波超声波组合法合成纳米氧化锌样品,运用X线粉末衍射(XRD)、透射电子显微镜(TEM)、扫描电子显微镜(SEM)及UV-Vis光谱对样品的组成及形貌进行表征.将纳米银与纳米氧化锌进行混合,采用菌落计数法测定混合物对大肠杆菌(E.coli)和金黄色葡萄球菌(S.aureus)的抑菌活性.结果表明,所合成样品为分散性好的5nm银颗粒及均一棱柱状结构的纳米氧化锌.二者混合物在银含量减少一半时对两种细菌的抗菌活性明显高于单独的纳米银或纳米氧化锌,表明混合物中纳米银和纳米氧化锌在抗菌时发挥了协同作用.

The nanostructures of silver （Ag） and zinc oxide （ZnO） were fabricated via reduction method at room temperature or microwave and ultrasonic combined technique. The compositions and morphologies of the products were characterized by powder X-ray diffraction （XRD）, transmission electron microscopy （TEM）, scan electron microscopy （SEM） and UV-Vis spectroscopy. The antibacterial activities of the mixture of nano Ag with nano ZnO against E. coli and S. aureus were measured by colony counting methods. The results showed that the products obtained were well dispersed Ag nanoparticles with size of 5 nm and homogeneous prism like nano ZnO. The antibacterial activity of the mixture of the nano Ag with the nano Zn（） against the two bacteria was apparent higher than that of nano Ag or nano ZnO alone at the concentration of Ag was reduced to the half. It indicated that there were synergistic antibacterial activities of the nano Ag with nano ZnO in the mixture.