低糖指数饮食降低冠心病发病风险的系统评价

Impact of low dietary glycemic index on decreasing of the risk of coronary heart disease： a system-atic review

目的评价低糖指数饮食对冠心病发病风险大小的影响。方法计算机检索2000年至2011年，Cochrane、JoannaBriggs（JBI）、Pubmed、EMbase、CBM、万方和CNKI中关于低糖指数饮食与冠心病发生的队列研究，同时筛检纳入文献的参考文献。由4名评价员对文献质量进行严格评价和资料提取，使用RevMan5．0软件对符合质量标准的队列研究进行Meta分析。结果纳入5篇英文文献，共128911例样本，方法学质量评价2篇为A级，其余3篇为B级。Meta分析结果显示低糖指数饮食是冠心病发生的危险因素RR值为1．25，RR95％CI为（1．13，2．15）。对男性和女性的结果进一步分析得出，低糖指数饮食只针对女性。危险因素RR值为1．35，95％CI为（1．16，1．57），而对于男性则并没有得到同样的结论RR值为0．96，95％C1为（0．76，1．31）。结论低糖饮食可以降低冠心病发生的风险，但对于男性是否同样适用，仍需要进一步的长期队列研究来提供证据。

Objective To evaluate the impact of low dietary glycemic index on the risk of coronary heart disease （CHD）. Methods We searched the Cochrane Database of Systematic Reviews, JBI Database of Systematic Reviews, MEDLINE, EMbase, CBMdisk,and CNKI to collect cohort studies from 2000 to 2011. The quality of cohort studies was critically appraised and data were extracted by 4 reviewers in- dependently. Meta- analysis were conducted for the eligible cohort studies using RevMan 5.0. Results Five cohort studies were included,and 128 911 samples were researched. The result of meta analysis indicated that low dietary glycemic index was a protective factor of CHD, RR value was 1.25,95% CI was （1.13,2.15）. Further more,the result was only effective to female, RR value was 1.35,95% CI was （1.16,1.57）, but not to male, RR value was 0.96,95%CI was （0.76,1.31 ）. Conclusions Low dietary glycemic index can decrease the risk of CHD,but it is still to be proved whether it is suitable to male.