摘要
目的研究神经酰胺合成酶(GCS)在肾癌组织中的表达及作用。方法采用Western-blot方法检测GCS在肾癌组织及癌旁组织中的表达情况。结果 GCS在肾癌组织中的表达明显高于癌旁组织(P<0.01)。结论 GCS在肾癌组织发生、发展过程中可能起重要的调控作用。
Objective To investigate the clinical role of glucosylceramide Synthase （GCS） in renal carcinoma. Methods Western-blot method was used to measure the protein expression of GCS in renal tumor tissue and normal tissue around the tumor. Results The expression of GCS in the tumor tissue was higher than that in the normal tis- sue around the tumor （P 〈 0.01 ）. Conclusion GCS play an important role in controlling the generation and progression of renal carcinoma.
出处
《肿瘤基础与临床》
2013年第1期9-10,共2页
journal of basic and clinical oncology
关键词
神经酰胺合成酶
肾癌
免疫蛋白印迹
glucosylceramide synthase
renal carcinoma
Western-blot
