多指标正交优选虫草养生宝胶囊的水提工艺

Optimization of Water Extraction Technology for Chongcao Yangshengbao Capsules by Multiple Indicator Orthogonal Test

目的:优选虫草养生宝胶囊的水提取工艺条件。方法:以粗多糖含量、HPLC指纹图谱共有峰相对峰面积总和及干膏得率为综合评价指标,采用L9(3)4正交试验设计,考察加水倍数、浸泡时间、提取时间3个因素对提取工艺的影响。结果:最佳水提取工艺条件为不浸泡,分别加8,6倍量水提取2,1.5 h。结论:优选的水提取工艺稳定可行。

Objective：To optimize water extraction technology conditions of Chongcao Yangshengbao capsules. Method： With extract yield,crude polysaccharide content and sum of relative peak area from common peaks of HPLC fingerprint as comprehensive evaluation index,orthogonal test was used to investigate effect of adding water muitiples,soaking time and extraction time on extraction process. Result： Optimum water extraction technology was as following：without soaking,extracted 2,1.5 h with 8,6 times the amount of water,respectively. Conclusion： This optimized extraction process was stable,reasonable and feasible.