虎皮楠内生真菌Aspergillus sp.DCS31化学成分研究

Chemical Constituents from the Endophytic Fungus Aspergillus sp. DCS31 of Daphniphyllum longeracemosum

从长序虎皮楠韧皮部分离到内生真菌Aspergillus sp.DCS31,经ITS序列分析将该株菌鉴定为曲霉属真菌。我们从该菌的固体发酵物中分离得到了5个化合物,经质谱和核磁共振波谱解析,分别鉴定为asperpyroneD(1)、asperpyrone A(2)、flavasperone(3)、1,2-benzenedicarboxylic acid bis(2α-methyl heptyl)ester(4)、2,5-di-hydroxyphenylacetic acid methyl ester(5)。化合物1、2、3、4为首次从虎皮楠内生真菌中分离得到。

Endophytic fungus Aspergillus sp. DCS31 was isolated from Daphniphyllum longeracemosum and identified to be AspergiUus by ITS sequence. Five compounds were isolated from the solid-state fermentation product of endophytic fungus Aspergillus sp. DCS31. Their structures were identified as asperpyrone D （1） ,asperpyrone A （2） ,flavasporone （3）, 1,2-benzene diearboxylic acid bis （2or-methyl heptyl） ester （4） and 2,5-dihydroxyphenylaeetie acid methyl ester （5）. Compounds 1-4 were isolated from the endophytie fungus of Daphniphyllum longeracemosum for the first time.