急性白毒伞蕈中毒致肝损伤的临床研究

Acute White Poison Umbrella Mushroom Poisoning Cause Liver Damage of Clinical Research

目的探讨急性白毒伞蕈中毒致肝损伤的临床特点和治疗方法。方法回顾分析该院收治的5例急性白毒伞草中毒患者的临床资料。结果急性白毒伞蕈中毒后均出现呕吐、腹泻、腹痛等明显的胃肠炎症状,进而出现严重并发症。5例患者中,2例入院时深度昏迷,抢救无效死亡,1例患者并发肝性脑病,终因肝功能、凝血功能严重损害被迫放弃抢救,于出院后次日死亡,其余2例患者救治成功,痊愈出院。结论应采用血浆置换为主的早期综合治疗法对急性白毒伞蕈中毒致肝损伤患者进行治疗。

Objective To study the acute amanita Verna mushroom poisoning induced liver injury： clinical characteristics and treatment methods. Methods Retrospective analysis of 5 cases of period from January 2010 to December 2011 admitted in our clinical data in patients with acute poisoning with amanita Verna grass. Results After acute poisoning by amanita Verna mushroom appear obvious gastroenteritis symptoms such as vomiting, diarrhea, abdominal pain, and serious complications. In 5 patients, 2 cases of admission, deep coma, rescuing died, 1 patients complicated with hepatic eucephalopathy, the end result of coagulation function of liver function, severe damage was forced to abandon the rescue, was discharged from hospital the day after the dead, and the remaining 2 cases of treatment of patients with, recovered and d!scharged. Conclusion Should be used early comprehensive treatment of plasma exchange on patients with hepatic injury induced by acute poisoning with amanita Verna mushroom for treatment.