细胞疗法——间充质干细胞在肾脏疾病中的应用

Cell therapy application of mesenchymal stem cells in kidney disease

细胞疗法是指依赖于细胞组织培养的方法扩充特殊的细胞用以代替疾病时分化紊乱的细胞，从而尽可能恢复正常的细胞功能。间充质干细胞（MSC）是一群具有自我更新、多向分化和高度增殖能力的未分化成熟细胞，是临床中应用最成熟的组织干细胞。间充质干细胞移植可以促进肾脏的恢复，通过向肾小球和肾小管细胞分化及促进肾脏分泌等机制对肾脏疾病起到治疗作用。

Objective Cell therapy depends on tissue and cell culture method to expand special cells instead of the differentiation derangement cells in disease, so as far as possible to restore normal cell function. Mesenchymal stem cell are mature ceils that possess the ability of self - renewal, multi - directional differentiation and altitude reproductivity, which are the most ripe tissue stem cell in the clinic application. Mesenchymal stem cell transplantation can promote many kidney recovery, treat kidney disease through mechanisms, such as differentiating to glomeruIar ceils and renal tubular ceUs, promoting kidney secretion and so on.