睡眠质量对高血压患者记忆功能障碍的影响

Effect of sleep quality on hypertension patients with dysmnesia

目的探讨高血压患者睡眠质量对其记忆功能障碍的影响。方法采取便利抽样的方法，选取2011年9—12月于唐山市工人医院心血管内科及高血压门诊就诊与病房住院的高血压病患者为调查对象。应用自行设计的问卷收集两组患者的一般资料，同时应用PSQI睡眠评测量表及RBMT．Ⅱ记忆测量量表分别对被调查患者的睡眠质量及记忆功能进行评测。评测后将记忆功能异常的高血压病患者纳入观察组（160例），选取同期记忆功能正常的高血压病患者160例为对照组，对两组高血压患者PSQI得分进行比较，就睡眠质量对高血压患者记忆功能影响行单因素Logistic回归分析。结果60．0％的记忆功能障碍的高血压患者睡眠质量差，而记忆功能正常的高血压患者仅有25．0％的人群睡眠质量差（F=8．717，P〈0．05）。记忆功能障碍组高血压患者睡眠质量总分明显高于记忆功能正常组[（10．23±4．0）比（5．88±1．60）分]，两组比较，差异有统计学意义（t=6．293，P〈0．01）。单因素Logistic回归分析结果显示，睡眠质量差的高血压患者患记忆功能障碍的危险是睡眠质量正常的高血压患者的4倍（OR：4．059，95％CI=1．568～10．510）。结论睡眠质量差是高血压患者患记忆功能障碍的危险因素，因此改善高血压患者的睡眠质量有助于缓解高血压患者记忆功能的下降。

Objective To discuss the influence of sleep quality on hypertension patients with dysmnesia. Methods Hypertension patients from Department of Cardiology and Hypertension in Tangshan Gongren Hospital from September to December 2011 were chosen by convenience sampling. Self-designed questionnaire was used to collect their data, Pittsburge sleep Quality Index （PSQI） and the rivermead behavicural memory test second edition ＇（ RBMT-II ） were used to assess their sleep quality and memory function. After assessment, patients with dysmnesia were included in the observation group, and patients with normal memory function were included in the control group. The effect of sleep quality on hypertension patients with dysmnesia was analyzed by logistic regression analysis. Results 60% hypertension patients with dysmnesia had poor sleep quality, and only 25% hypertension patients with normal memory function had poor sleep quality. The score of PSQI was much higher in the observation group than in the control group [ （ 10.23 ±4.0） vs （5.88 ± 1.60） ], and the differences was statistically significant （t =6. 293 ,P 〈0. 01 ）. Single factor logistic regression analysis showed that hypertension patients with poor sleep quality had 4 times higher risk of dysmnesia than those who had normal sleep quality （ OR = 4. 059, 95% CI = 1. 568 - 10.510）. Conclusions Poor sleep quality was a risk factor of dysmnesia to hypertension patients, therefore improving sleep quality in hypertension patients is helpful to ease their decrease of memory function.