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98例肺结核患者IL-10和IL-6表达水平的临床研究 被引量:8

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摘要 目的探讨肺结核患者IL-10和IL-6表达水平改变情况及其意义。方法选择该院2009年2月—2012年2月肺结核患者98例,作为肺结核组。同时选择同期到该院体检的健康者共98例,作为对照组。肺结核患者在入院后第2天、在化疗4周后清晨空腹抽取静脉血2mL、所选98例健康者在体检当天早晨空腹取静脉血2mL,分别测定测定血清IL-6和IL-10水平。结果肺结核患者化疗前IL-6水平显著高于对照组(P<0.05);肺结核患者化疗后IL-6水平高于对照组(P<0.05);肺结核患者化疗前IL-6水平高于化疗后(P<0.05)。肺结核患者化疗前IL-10水平高于对照组(P<0.05);肺结核患者化疗后IL-10水平与对照组比较,差异无统计学意义(P>0.05);肺结核患者化疗前IL-10水平高于化疗后(P<0.05)。结论肺结核患者在抗结核治疗前炎症反应强烈,促炎因子和抑炎因子均表达强烈,抗结核治疗后促炎因子和抑炎因子均表达降低,炎症反应减弱。
作者 黄斌
机构地区 彭湃纪念医院
出处 《中外医疗》 2013年第3期27-28,共2页 China & Foreign Medical Treatment
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