阿仑膦酸钠联合注射用骨肽及钙尔奇D治疗骨质疏松症的疗效及安全性

Alendronate Sodium Injection Combined with Bone Peptide and Calcium's odd D the Treatment of Osteoporosis Safety and Efficacy

目的探讨2种方案治疗老年骨质疏松症的疗效。方法选取来该院经检查骨质疏松T值〈-2的60例受试者,将以上患者随机分为两组。西药组（A组）：依降钙素（10U/次,2次/周,肌注）单药连续使用3个月后,注射组（B组）：阿仑膦酸钠联合注射用骨肽及钙尔奇D联用连续使用21个月。结果两组BMD均呈上升趋势,治疗12个月后下降趋势改变呈上升趋势。两组BMD的变化值比较,在L1、L2~4和髋全部比较差异有统计学意义（P〈0.05）,其余部位,差异无统计学意义（P〉0.05）。两组比较差异有统计学意义（P〈0.05）。结论 2种方治疗骨质疏松症均有疗效,西药组治疗作用缓慢,注射组治疗作用快,而且疗效比较持久。

Objective Observation of curative effect on senile osteoporosis treated with 2. Methods Western Group （group a）： depending on the calcitonin （10 U/times, 2 times/week, intramuscular） monotherapy continuously for 3 months after the injection Group（Group b）： Alendronate Sodium for injection combined with bone calcium peptide and odd d continuously for 21 months. Results Comparison between two groups differences are statistically significant （P〈0.05）. Conclusion 2 kinds of therapeutic effect of treatment of osteoporosis is,Western medicine treatment role slowly injecting tissue treatment and rapid, and effect of a more durable.