期刊文献+

利多卡因治疗慢性喘息型支气管炎急性发作的疗效观察 被引量:11

下载PDF
导出
摘要 目的探索利多卡因在治疗慢性喘息型支气管炎急性发作中的疗效。方法选取在该院治疗慢性喘息型支气管炎患者90例,将其随机分成两组,治疗组和对照组,对照组患者给予常规治疗,选用氧速为8~10L/min氧气做动力的雾化器,治疗组给予雾化生理盐水3次/d,10mL/次,连续治疗5d;治疗组患者给予利多卡因治疗,选用相同的仪器将利多卡因雾化,给予治疗组患者给予雾化利多卡因3次/d,给予2%100mg/次。在治疗的过程中观察两组患者1秒用力呼吸容积、心率、动脉血压值、最大呼吸量、二氧化碳分压值及呼吸频率等。结果通过观察和比较两组患者吸入雾化药物前后,对照组的呼吸频率和心率较治疗组明显降低,治疗组患者1秒呼吸容积值明显比对照组增强,比较两组患者二氧化碳分压值的降低程度和动脉血压升高程度,治疗组明显比对照组变化显著,对照组的不良反应发生率明显低于治疗组。结论雾化吸入利多卡因在治疗慢性喘息型支气管炎急性发作中发挥着积极性的作用,疗效明显,同时在缓解患者喘息症状方面有显著明确的疗效。
作者 孙莉娜
出处 《中外医疗》 2013年第3期106-107,共2页 China & Foreign Medical Treatment
  • 相关文献

参考文献3

二级参考文献15

  • 1钟南山,徐军.哮喘发病机制及诊断新进展(现代呼吸系疾病系统讲座第五讲)[J].中华结核和呼吸杂志,1995,18(3):136-139. 被引量:168
  • 2中华医学会呼吸病学分会哮喘学组.支气管哮喘防治指南(修订稿)[J].中华结核和呼吸杂志,1993,16:5-8.
  • 3[5]Enrigth PL,Mc Nally F,Souhrada JF.Effect of lidocaine on the ventilarory and airway responses to exercise in asthmatics.Am Rev Respir Dis,1980,122(6):823-828
  • 4[6]Okada S,Hagan JB,Kato M,etal.Lidocaine and its analogues inhibit IL-5 mediated survival and activation of human eosinophils.J Immunol,1998,160(8):4010-4017
  • 5Hunt LW. Effect of nebulized lidocaine on severe glucocoricoid- dependent asthma. Mayo Clin Proc, 1996, 71(4):361.
  • 6Groeben H. Combined intravenous lidocaine and inhaled salbutamol protect against bronchial hyperreactivity more effectively than lidocaine or salbutamol alone. Anesthesiology, 1998, 89(4) :862.
  • 7Groeben H. Both intravenous and inhaled lidocaine attenuate reflex bron-choconstriction but at different plasma concentrations. Am J Respir Crit Care Med, 1999, 119(2):530.
  • 8Decco ML. Nebulized lidocaine in the treatment of severe asthma in children apilot study. Ann Allergy Asthma Immunol, 1999, 82(1):29.
  • 9Groeben H, Silvanus MT, Beste M, et al. Both intravenous and inhaled lidocaine attenuate reflex bronchoconstriction but at different plasma concentrations. Am J Respir Crit Care Med, 1999,159: 530-535.
  • 10Decco ML, Neeno TA, Hunt LW, et al. Nebulized lidocaine in the treatment of severe asthma in children: a pilot study. Ann Allergy Asthma Immunol,1999, 82: 29-32.

共引文献20

同被引文献54

  • 1刘春江,张江宇,蔡小灵.利多卡因雾化吸入对哮喘急性发作疗效的临床观察[J].国际医药卫生导报,2006,12(2):26-27. 被引量:14
  • 2杨华,杨发文,黄曜勇.应用利多卡因对慢性喘息型支气管炎患者进行雾化治疗的疗效观察[J].当代医药论丛,2014,12(1):285-285. 被引量:5
  • 3高小峰,孙颖浩,王林辉,许传亮,高旭,盛夏,侯建国.利多卡因加布比卡因局部麻醉在前列腺穿刺活检术中的应用[J].中华泌尿外科杂志,2007,28(9):619-622. 被引量:6
  • 4陆再英,钟南山.内科学[M].7版.北京:人民卫生出版社,2008:775.
  • 5Chang HYS,Togias A,Brown Ell. The effect of systemic lidocaine on air-way tone and pulmonary function in asthmatic subjects[J].Anesth Analg, 2007 104(5):1109-1115.
  • 6Man SF, McAlister FA,Anthonisen NR,et al.Contemporary management of chronic obstructive pulmonary disease:clinical applications[J].Jama,2003,290:2313-2316.
  • 7CF Chong,CC Chen,HP Ma,et al.Comparison of lidocaine and bronchodilator inhalation treatments for cough suppression in patients with chronic obstructive pulmonary disease[J].Emerg Med J,2005,22(6):429-432.
  • 8Groeben H,Foster WM,Brown RH.Intravenous lidocaine and oral mexileline block reflex bronchoconstrtion in asthmatic subj- ects[J].Am J Respir Crit care Med, 1996($4):885-888.
  • 9Chang HYS,Togias A,Brown RH.The effectd of systemic lidocaine on airway tone and pulmonary function in asthmatic subjects[J].Anesth Analg,2007,104(5): 1109-1115.
  • 10周立字,刘军平.亚甲蓝与利多卡因混合剂改善痔外剥内扎术后疼痛的临床观察[J].健康必读·中旬刊,2012(9):237-238.

引证文献11

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部