2010～2012年泰安市腹泻婴幼儿轮状病毒感染情况分析

Analysis of the status of rotavirus infection among infants with diarrhea in Tai'an from 2010 to 2012

目的了解腹泻婴幼儿轮状病毒(RV)感染情况并探讨其发病特点,为临床诊治提供依据。方法采用胶体金法检测就诊的腹泻婴幼儿粪便标本RV,并对结果进行分析。结果 8 998例腹泻婴幼儿,粪便标本RV阳性2 873例,阳性率为31.93%;2010和2011年10～12月份阳性率最高,分别为35.85%和41.65%,1～3月份阳性率分别为32.54%和35.11%;1～2岁患儿RV阳性率最高,达36.85%;男童与女童RV阳性率分别为32.67%和30.98%,差异无统计学意义(P>0.05);2 873例阳性标本中脂肪球阳性37.28%。结论 1～2岁婴幼儿是RV感染的高危人群;RV感染有明显季节性,高发于每年的10月到次年3月。

Objectives To investigate the status of group A rotavirus （RV） infection among infants with diarrhea in Tai ＂an, explore the characteristics of the disease, and provide a corresponding basis for clinical diagnosis and treatment. Methods The colloidal gold method was used to test stool from infants with diarrhea at this hospital and the results of the test were analyzed. Results Of 8 998 samples, 2 873 were positive for RV at a rate of 31.93%. Positivity was greatest from October to December in 2010 （35.85%） and 2011 （41.65%）, while positivity from January to March was 32.54% in 2010 and 35.11% in 2011. Positivity was greatest among infants ages 1--2 years, reaching 36.85%. Positivity was the same for boys and girls （32.67% vs. 30.98%）, and samples tested positive for fat globules at a rate of 37. 28%. Conclusion Infants 0--3 years old are at risk for RV infection. The infection had significantly seasonality, with most infections occurring from November to March of the following year.