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瑞舒伐他汀治疗老年冠心病的临床疗效观察 被引量:5

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摘要 目的观察组瑞舒伐他汀治疗老年冠心病的临床效果。方法选取我院治疗的冠心病合并高脂血症患者114例,随机分为治疗组和对照组,每组有患者57例。治疗组给予瑞舒伐他汀治疗,对照组给予辛伐他汀治疗。观察两组患者血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)和高密度脂蛋白(HDL-C)及不良反应。结果治疗组患者治疗的总有效率为84.2%(48/57)明显高于对照组的总有效率61.4%(35/57),且差异有统计学意义(P<0.05)。治疗前,两组换装的血脂指标(TC、TG、LDL-C和HDL-C)比较,无明显差异,无统计学意义(P>0.05)。治疗后,治疗组患者的TC、TG和LDL-C均有不同程度的降低,且与治疗前比较,差异明显,有统计学意义(P<0.05);对照组患者的TC和LDL-C均有不同程度的降低,且与治疗前比较,差异明显,有统计学意义(P<0.05)。结论瑞舒伐他汀治疗老年冠心病能显著降低患者的TC、TG和LDL-C,并未见严重不良反应,安全性好,值得临床应用。
作者 应业杰
出处 《海峡药学》 2013年第2期198-199,共2页 Strait Pharmaceutical Journal
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