摘要
目的 :开发慢性动物实验的理想麻醉剂。方法 :以传统麻醉剂戊巴比妥钠为对照 ,应用静松灵氯胺酮合剂对 32只豚鼠进行听脑干反应 (auditorybrainstemresponse ,ABR)测试。结果与结论 :与戊巴比妥钠相比 ,氯胺酮静松灵合剂具有起效迅速、ABR测试完毕后苏醒快、死亡率低等优点。
Aim: To look for a satisfying anesthetic for chronic animal experiment. Methods:Experimental group and control group were anesthetized by jingsongling ketamine mixture and pentobartitone respectively and all the guinea pigs were tested of auditory brainstem response (ABR). Results and Conclusion: The results revealed that jingsongling ketamine mixture worked faster, and had a shorter awaking duration after the test and a lower death rate than pentobartitone did while ABR testing results were consistent between the 2 groups.
出处
《河南医科大学学报》
2000年第6期489-490,共2页
Journal of Henan Medical University
基金
河南省教委自然科学研究基金资助93470055
关键词
氯胺酮
静松灵
听脑干反应
豚鼠
ketamine
jingsongling
auditory brainstem response
guinea pig
