1994年～1998年太原地区夏季急性感染性腹泻菌群及耐药性变迁研究

A study on the flora of acute infectious diarrhea and their changes of drug resistance in the summers from 1994 to 1998 in Taiyuan

目的 :探讨 1994年～ 1998年本市夏季急性感染性腹泻主要致病菌群、抗生素敏感谱及耐药性的变化。方法 :取脓血便做培养 ,用 S.S、麦康凯及山梨醇培养基 ,对培养阳性菌株做病原菌分离和菌群鉴定 ,并做 10余种抗生素敏感试验。结果 :福氏痢疾杆菌为主要致病菌。细菌对抗生素有较高耐药性 ,且呈多重耐药。五年中 ,氟哌酸、痢特灵、先锋霉素 、卡那霉素、庆大霉素、丁胺卡那霉素、氨苄青霉素的耐药性呈显著性变化。环丙沙星较氟哌酸耐药率低 ,但二者无显著性差异。

Objective:To study the main pathogenic flora of acute infectious diarrhea,their sensitive spectrum to antibiotics,and their changes of drug resistance in the summers from 1994 to 1998 in Taiyuan.Method:The bloody purulent stool was cultured in the medium of S.S,Maikangkai and sorbitol.Pathogen separation,flora assay and the sensitive test to more than 10 kinds of antibiotics were done among the positive strains.Result:Shigella flexneri was the main pathogen.The bacteria had high drug resistance to antibiotics,and with the attribute of multidrug resistance.In the 5 years,the drug resistance of Norfloxacin,Furazolidon,Cefazolin,Kanamycin,Gentamycin,Amikacin and Ampicillin changed evidently.The drug resistance rate of Ciprofloxacin was lower than Norfloxacin,but there was no significant difference between them.