系统性硬皮病的肺部病变

Pulmonary disorders in systemic sclerosis

为了解系统性硬皮病 (SSc)病人肺部病变情况，对 176例 SSc病人 (均无肺部病变的临床表现 )作胸片和肺功能检查，并与 32例局限性硬皮病 (LSc)患者及 469名正常体检者作对照。结果 SSc组肺部病变发生率为 89.8％，显著高于 LSc组 (28.1％ )及正常人群组 (13.4％ )(P< 0.01)， SSc组Ⅰ、Ⅱ、Ⅲ型间肺部病变发生率无显著性差异 (P >0.05)。本文结果提示肺部病变是 SSc常见并早期发生的内脏损害，宜常规作胸片及肺功能检查。

To explore pulmonary disorders of the patients with systemic sclerosis(SSc),chest X- ray film and pulmonary function were examined in 176 patients with SSc who had no clinical manifestations of pulmonary disease and compared with 32 patients with local scleroderma(LSc) and 469 normal controls. Results: Morbidity of pulmonary disorders in the patients with SSc (89.8％ ) was significantly increased than in the patients with LSc(28.1％ )(P< 0.01)and in normal controls(13.4％ (P< 0.01). The level of morbidity in pulmonary disorders showed no statistical differences among the patients ofⅠ、Ⅱ andⅢ types(P >0.05). Pulmonary disorder was common and early internal phenomenon of patients with SSc. We should routinely examine chest X- ray and pulmonary function of the patients with SSc.