汗孔角化瘤一例

Porokeratoma： a case report

报告1例汗孔角化瘤。患者男，35岁。双臀部发生疣状结节1年余，无痛痒。第1次就诊时双臀部各有1个豌豆大疣状结节，手术切除3个多月后又在原部位复发。第2次就诊时共有4个（左臀1个，右臀3个）类似疣状结节。组织病理：主要表现为棘层肥厚和致密正角化过度，内有数个宽大的鸡眼样角化板。诊断为汗孔角化瘤。再次手术切除，术后给予阿维A口服，随访15个月未复发。

A case of porokeratoma is reported. A 35-year-old man presented with asymptomatic verrucous nodules on both buttocks for more than 1 year. Skin examination at the first visit revealed two pea-sized verrucous nodules on bilateral buttocks. The lesions recurred at the primary site 3 months after surgical resection. At the second visit, there were 4 verrueous nodules, including 1 on the left buttock and 3 on the right buttock. Histopathological examination showed a well-defined lesion characterized by acanthosis and compact, thick orthokeratosis with seveal broad cornoid lamellae. A diagnosis of porokeratoma was made. The lesion was resected again followed by oral aeitretin treatment. No recurrence was observed during 15 months of follow up.