经阴道彩色多普勒超声检测先兆流产妊娠黄体的形态和血流变化的研究

Detecting morphologic and blood flow changes of corpus luteum of pregnancy by transvaginal color doppler ultrasound in pregnant women with threatened abortion

目的探讨先兆流产经阴道彩色多普勒超声检测妊娠黄体的形态和血流的变化。方法选择该院2010年8月—2012年3月产科门诊就诊的先兆流产且有生育要求者79例,其中不能维持妊娠者41例作为观察I组,能维持妊娠者38例作为观察II组,另选取该院在此期间的正常早孕要求人流者79例作为对照组,经阴道彩色多普勒超声检查并观察比较三组妊娠黄体的内部回声情况、黄体平均直径及其血流动力学参数峰值流速(PSV)及阻力指数(RI)值。结果三组妊娠黄体均以不均质性低回声团块型最为常见,其次为厚壁囊性结构型,三组妊娠黄体回声类型比较,差异无统计学意义(P>0.05)。观察I组黄体平均直径明显小于观察II组和对照组,差异有统计学意义(P<0.05)。观察II组与对照组比较,差异无统计学意义(P>0.05)。观察I组PSV明显低于观察II组和对照组,RI明显高于观察II组和对照组,差异有统计学意义(P<0.05)。观察II组与对照组PSV和RI比较,差异无统计学意义(P>0.05)。结论先兆流产经阴道彩色多普勒超声检测黄体形态、血流的变化对判断先兆流产预后具有重要的价值。

Objective To investigate morphologic and blood flow changes of corpus luteum of pregnancy by transvaginal color doppler ultrasound in pregnant women with threatened abortion. Methods 79 outpatients with threatened abortion admitted to out hospital from Aug. 2010 to Mar. 2012 were selected and divided into observation group Ⅰ （n=41） and observation group Ⅱ （n-38） according to whether maintainable pregnancy or not. 79 volunteers with normal intrauterine gestation were served as control group. The echogenicity, mean luteal diameter, peak systolic velocity （SV）and resistance index （RI）were detected comapred among the three groups. Results There were no significantly difference of the hypoechoic structure among the three groups （P〉0.05）. The mean luteal diameter of the observation group Ⅰ was smaller than that of the observation group II and control group （P〈0.05）. The peak systolic velocity of the observation I was significanly lower than that of the bservation group II and control group （P〈0.05）. The resistance index of of the observation I was significanly lower than that of the observation group Ⅱ and control group （P〈 0.05）. Conclusion Detecting morphologic and blood flow changes of corpus luteum of pregnancy by transvaginal color doppler ultrasound has important value in predicting prognosis of threatened abortion.