莫沙必利对人胃黏膜上皮细胞的保护作用及其机制
摘要
胃肠道不良反应是阿司匹林预防心脑血管疾病面临的主要问题。有研究指出莫沙必利有胃黏膜保护作用。阿司匹林损伤人胃黏膜细胞的机制与细胞外信号调节激酶（extracellular signal-regulated kinase, ERK）有关。本研究将莫沙比利作用于被阿司匹林损伤的胃黏膜上皮细胞，测定其对磷酸化-ERK（p-ERK）1／2表达的影响，探讨莫沙比利对胃黏膜的保护机制是否与ERK传导通路有关。一。
出处
《中华消化杂志》
CAS
CSCD
北大核心
2013年第2期119-120,共2页
Chinese Journal of Digestion
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