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原发性肝癌血清中高尔基体蛋白73的表达及其与预后的关系 被引量:7

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摘要 原发性肝癌是临床上最常见的恶性肿瘤之一,在我国发病及病死率相当高。由于肝癌组织血供丰富,很多患者术前就已存在微转移,术后就更容易发生复发转移。因此,只有早期诊断及早期治疗才能改善肝癌患者预后。高尔基体蛋白73(Golgiprotein-73,GP73)是近年来发现的有关肝损害的新指标,尤其在肝细胞癌(hepatocellular carcinoma,HCC)中改变特别明显,甚至有文献报道GP73可以作为HCC的标志物。本研究探讨血清GP73蛋白水平与原发性肝癌肝损害严重程度、术后复发及生存预后的关系,为临床上及时有效的治疗提供一定的实验基础。一。
出处 《中华消化杂志》 CAS CSCD 北大核心 2013年第2期132-133,共2页 Chinese Journal of Digestion
基金 国家自然科学基金(81000176/H0317) 浙江省自然科学基金(Y2090326、Y2110634) 王宝恩肝纤维化研究基金(20100002)
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