HIV感染并发带状疱疹12例临床分析

Clinical Analysis of 12 HIV-infected Patients with Herpes Zoster

目的探讨HIV感染者并发带状疱疹的临床特点。方法回顾性分析2008年11月-2011年10月本科收治的12例HIV感染并发带状疱疹患者的临床资料。结果男9例,女3例;年龄25～58岁,大于50岁1例。农民8例,工人1例,个体2例,职员1例。11例皮损分布≥2个神经分支支配区,均出现神经痛症状,其中5例疼痛明显。临床治愈11例,好转1例。三年间检出HIV感染并发带状疱疹者分别为2例、4例和6例。结论 HIV感染者易并发带状疱疹,带状疱疹可为HIV感染的首要症状。HIV感染并发带状疱疹者神经痛症状明显,皮疹累及范围较大,治疗上不用糖皮质激素,可常规予抗病毒、营养神经、消炎止痛、免疫调节等,一般疗效满意。

Objective To explore the clinical characteristics of HIV-infected patients with herpes zoster. Methods A retrospective analysis was performed on patients diagnosed as HIV infection with herpes zoster from November 2008 to October 20ll in our hospital. Results There were 12 HIV-infected patients with herpes zoster, male nine cases, female three cases, aged 25 to 58 years, average 35 years old. Eight cases were farmers, one was worker, two cases were individual and the other one was company staff. All the patients had neuropathic pain syndromes, five cases of them paining obviously. Patients were all with the two nerve branches innervating the area except one. 11 cases were cured, the other one was better. There were two cases of HIV patients diagnosed in the first year, four cases in the second year and six cases in the third year. The incidence of HIV increased with year. Conclusion HIV infection complicated with herpes zoster easily. Herpes zoster should be recognized as a marker condition indicating the necessity of screening for HIV. Obviously neuropathic pain and larger scale of rash always occurred in the HIV patients with herpes zoster. The common treatment of HIV patients with herpes zoster were using medicine with antivirus, nerve nutrition, diminishing inflammation acetanilide and enhancing immunologic function, but not glucocorticoid. The treatment alleviated the symptom effectively.