花斑癣样疣状表皮发育不良伴鳞状细胞癌1例

A Case of Epidermodysplasia Verruciformis of Tinea Versicolor’s Type with Squamous Cell Carcinoma

患者女,41岁。颈部、躯干淡红色斑30余年,左颞近眉弓处结节6个月。背部皮损组织病理示:表皮角化过度伴角化不全,棘细胞层上部可见空泡化细胞,真皮浅层见散在的炎细胞浸润;左颞部皮损组织病理示:真皮内可见大量鳞状细胞组成的呈团块状分布的肿瘤灶,瘤细胞核大浆少明显异型性,肿瘤灶间质内血管增生扩张,弥漫炎细胞浸润。诊断:花斑癣样疣状表皮发育不良伴左颞部鳞状细胞癌。

A 41-years-old female patient presented with trunk and neck flat maculopapule for 30 years, with nodule-like ulceration on the left temporal besides glabellar reflex for 6 months. Histopathological examination of the back showed epidermis hyperkeratosis and parakeratosis, the ballooning degeneration could be seen in the upper part of the stratmn spinosum, inflammatory ceil infiltration in derma. Histopathological examination of the left tempus showed tumor group was composed of squamous cells in the upper of dermis, the tumor cells with big cell nucleus and less cytolymph obvious atypia, vascular proliferation expansion in tumor mesenchyme, and contain inflammatory cells. Diagnosis ： Epidermodysplasia verruciformis of tinea versicolor＇ s type with squamous cell carcinoma of left temporal.