生殖支原体检测方法研究进展

Advances in the Laboratory Diagnosis of Mycoplasma Genitalium

生殖支原体是引起非淋菌性尿道炎和宫颈炎的常见病原体之一。生殖支原体分离培养极为困难,而血清学检测缺乏特异性,这些均阻碍了其临床研究。随着分子生物学的发展,聚合酶链反应技术因其具有较高的敏感性和特异性而成为生殖支原体感染基础和临床研究的主要手段。

Mycoplasma genitalium is a common cause of nongonococcal urethritis （cervicitis）. As a fastidious bacterium, M. genitalium is very difficult and time-consuming to culture. The lack of specificity for the serological tests also hampers the clinical research of M. genitalium. With the development of molecular biology, polymerase chain reaction tests, which have high sensitivities and specificities, have become the main tools for the foundational and clinical researches of M. genitalium.