超声造影评价腹膜后动脉出血的实验研究

An experimental study of contrast enhanced ultrasound in the evaluation of retroperitoneal arterial hemorrhage

目的:探讨超声造影对腹膜后动脉损伤出血的诊断价值。方法:5只实验兔,直接穿刺法建立腹膜后髂外动脉活动性出血模型,创伤后2 min、10 min及40 min分别行超声造影观察,创伤后20 min、30 min两次行DSA检查,作为金标准评价损伤动脉出血情况。结果:动脉损伤2 min时行静脉造影检查,可动态观察造影剂自动脉破口处溢出至腹膜后呈"喷射状",于动脉破口处测得高速血流,动脉损伤后10 min、40 min重复行静脉造影检查,仍可见造影剂自破口处渗出,但流速明显减慢,与DSA检查结果一致。结论:超声造影能准确显示腹膜后动脉活动性出血部位及流速,有较好的临床应用前景。

Objective： To explore the value of contrast-enhanced uhrasonography （CEUS） in the diagnosis of retroperitoneal arterial hemorrhage. Methods： Five active bleeding sites were created in the external iliac artery of five rabbits. CEUS was used to observe the feature of active bleeding 2 rain, 10 min and 40 min after the arterial injury. DSA was also used at 20 min and 30min after the arterial injury, as a gold standard. Results： 2 rain after the arterial injury, CEUS showed active bleeding sites with the feature of jet-like and high flow at the bleeding point. At 10 min and 40 min after the arterial injury, CEUS showed the feature of seeping-out and lower speed flow than before. The results were consistent with DSA. Conclusion： CEUS can display active bleeding of retroperitoneal arterial injury, and it will have good prospects for clinical application.