1Blackbum EH.Structure and function of telomercs[J].Nature,1991,350:569.
2Harley CB,Futeher AB, Greider CW. Telomerea aborten during ageing of human fiboroblasts[J].Nature, 1990,345 (6274) :458.
3Greider CW, Blackburn EH. Identification of a specific telomere teriminal transferase activity in Tetrahymena extrscts[J] .Ce11.1985,43:405.
4Lindsey J,Me Cill N, Lindsey LA.et al. In vivo lesa of telomeric repeats with age in human[J] .Murat Res, 1991,85(1):245.
5Krnk PA, Rampino NJ.Bohr VA.DNA damage and repair in telomeres.Relation to aging[J].Proc Natl Acad Sci USA, 1995,92:258.
6Kim NW, Piatyszek MA,Prowse KR, et al.Specific association of human telomerase activity with inmotal cells and cancer[J] .Science, 1994, 266 :2011.
7Kitada T,Seki S, Kawakita N, et al.Telamere shortening in chranic Liver disewes[J].Bioch-Bioph Res Comm,1995.211(1):33.
8Ogami M, Ikuru Y,Niduguehi S, et al. Quantitative analysis and in situ lucalization of human telomerase RNA in chromic liver disease and hepatucelluar carcinoma[J]. Lab-invest,1999,79(1) : 15.
9Ohashi K,Tsutsumi M,Nukajima Y,et al.Telomerase changes in human hepatocellular carcinones and hepatitis virus infected noncancenous livers[J],Cancer,1996.77:1747.
10Kojimu H, Yokosuka O,Imazeki F,et al.Telomerase activity and telozaere length in hepatocellular carcinoma and chmtric liver disease[J]. Castroeaterology. 1997,112 : 493.
4Tahara H,Nakanishi T,Kitamoto M.Telomerase:activity in human liver tissue comparison between chronic liver disease and hepatocellular carcinomas[J].Carcinomas,1995,55:2374-2376.
5Kazuhiro N,Yoshihiro U,Toshihiro H.Telomerase as a tool for the differential diagnosis of human hapatocellular carcinoma[J].Cancer,1996,78:232-236.
6Arii S,Mise M,Harada T,et al.Overexpression of matrix metalloproteinase-9 gene in hepatocellular carcinoma with invasive potential[J].Hapatology,1996,24(2):316-319.
7Okazaki L,Wada N,Nakano M,et al.Difference in gene expression for matrix metalloproteinase-1 between early and hepatocellular carcinomas[J].Hepatology,1997,25(3):580-584.
8Hayasaka A,Suzuki N,Fujimoto N,et al.Elevated plasma levels of matrix metalloproteinase-9(92kD type collagenase/gelatinase B) in hepatocellular carcinoma[J].Hepatology,1996,24 (5):1058-1062.