代谢综合征影响卵母细胞质量研究

Effect of metabolic syndrome on oocyte quality

代谢综合征是以多种代谢性危险因素聚集为特征的临床症候群,与肥胖和胰岛素抵抗有着十分密切的关系,已经成为卵母细胞质量下降的重要因素。代谢综合征的并发症影响着育龄期妇女,部分与肥胖和多囊卵巢综合征的特征一致,继发性的可引起不孕和不良的生殖结局。代谢综合征影响生殖功能的机制在于肥胖和胰岛素抵抗引起卵母细胞质量下降。

Metabolic syndrome is a characteristic clinical syndrome in different metabolic risk factors gathered, and is strongly associated with obesity and insulin resistance, has become a important factor of decline in the oocyte quality. The complications of metabolic syndrome affects women of reproductive age, women of reproductive age are not spared from the complications of metabolic syndrome, which overlaps with obesity and polycystic ovary syndrome, both of which are linked to infertility and poor reproductive outcome. Effect of metabolic syndrome on reproductive function is the mechanism of obesity and insulin resistance causing oocyte quality decreased.