苯那普利与卡托普利治疗肾性高血压的疗效对比

Comparison of Benazepril and captopril in treatment of renal hypertension

目的 :比较苯那普利与卡托普利治疗肾性高血压的降压效应与安全性。方法 :84例肾性高血压患者随机接受苯那普利 (10～ 2 0 mg/ d)与卡托普利 (37.5～ 75.0 mg/ d) (各 4 2例 )治疗 4周。结果 :苯那普利与卡托普利的降压总有效率在偶测血压监测时分别为 92 .5%和 90 .5% ,两组降压疗效比较无显著性差异 (P>0 .0 5) ,两组治疗前后血压比较均有显著性差异 (p<0 .0 0 1) ,但两组之间降压幅度比较无显著性差异 (p>0 .0 5) ;结论 :苯那普利对肾性高血压疗效较好而且安全。

Objective:[WT5BZ]To compare the effect and safeness of benazepril and captopril in treatment of renal hypertension.[WT5HZ]Method:[WT5BZ]Benazepril(10～20mg/d)and captopril(37.5～75.0mg/d)were given to two groups(each 42) of renal hypertensions for treatment for 4 weeks.[WT5HZ]Result:[WT5BZ]The data of casual use of blood pressure monitor showed that the benazepril group the effective rate was 92.5%.Whereas the captopril group,the effective rate was 90.5%.And there was little difference between the two groups in curative effect and rang of decreasing blood pressure(p>0.05),but the blood pressure before and after treatment were obiviously different(p<0.001).[WT5HZ]Conclusion:[WT5BZ]Benazepril is more effective and safe in the treament of renal hypertension. [WT5HZ]